Publications
A comprehensive dataset of annotated brain metastasis MR images with clinical and radiomic data
Ocaña-Tienda B, Pérez-Beteta J, Villanueva JD, Romero JA, Molina D, Suter Y, Asenjo B, Albillo D, Ortiz A, Pérez-Romasanta LA, González E, Llorente M, Carballo N, Nagib F, Vidal M, Luque B, Reyes M, Arana E, Pérez-García VM
Scientific Data 10, 208 (2023)
Analytical performance validation of aPROMISE platform for prostate tumor burden
García Vicente, A.M., Lucas Lucas, C., Pérez-Beteta, J. et al.
Scientific Reports 14, 3001 (2024)
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression
O Molina, C Ortega-Sabater, N Thampi, N Fernández, M Guerrero, A Martínez, M Vinyoles, T Velasco, C Bueno, JL Trincado, I Granada, D Campos, C Giménez, JM Boer , ML den Boer, GF Calvo, Mireia Camós, JL Fuster P Velasco, P Ballerini, F Locatelli, CG Mullighan, DCJ Spierings, F Foijer, VM Pérez-García, P Menéndez
EMBO Molecular Medicine 16, 64-92 (2024)
Deterministic reprogramming of neutrophils within tumors
M.S.F. Ng, I. Kwok, L. Tan, C. Shi, D. Cerezo, Y. Tan, K. Leong, G.F. Calvo, K. Yang, Y. Zhang, J. Jin, K.H. Liong, D. Wu, R. He, ..., A. Hidalgo, F. Ginhoux, L.G. Ng
Science 383, eadf6493 (2024)
Growth exponents reflect evolutionary processes and treatment response in brain metastases
B. Ocaña-Tienda, J. Pérez-Beteta, D. Molina-García, J. Jiménez-Sánchez, O. Leon-Triana, A. Ortiz de Mendivil, B. Asenjo, D. Albillo, L. Pérez-Romasanta, M. Valiente, L. Zhu, P. García- Gómez, E. González-Del Portillo, M. Llorente, N. Carballo, E. Arana, V. M. Pérez-García
npj Systems Biology and Applications 9, 35 (2023)
Mathematical Modeling of Leukemia Chemotherapy in Bone Marrow
Ana Niño-López, Salvador Chulián, Álvaro Martínez-Rubio, Cristina Blázquez-Goñi, María Rosa
Mathematical Modelling of Natural Phenomena 18, 21 (2023)
Mean first-passage time of cell migration in confined domains
H. Serrano, R.F. Álvarez-Estrada, G.F. Calvo
Mathematical Methods in the Applied Sciences 46, 7435-7453 (2023)
Metabolic Activity Grows in Human Cancers Pushed by Phenotypic Variability
J.J. Bosque, G.F. Calvo, D. Molina-García, J. Pérez-Beteta, A.M. García Vicente, V. M. Pérez-García
iScience 26(3) 106118 (2023)
On the Analysis of a Mathematical Model of CAR-T Cell Therapy for Glioblastoma: Insights from a Mathematical Model
Bodnar, M ; Forys, U ; Piotrowska, MJ ; Bodzioch, M ; Romero-Rosales, JA; Belmonte-Beitia, J
International Journal of Applied Mathematics and Computer Science 33(3), 379-394 (2023)
On the Dynamics and Optimal Control of a Mathematical Model of Neuroblastoma and its Treatment: Insights from a Mathematical Model
José García Otero, Mariusz Bodzioch, and Juan Belmonte-Beitia
M3AS: Mathematical Models and Methods in Applied Sciences 07(34) (2024)
Overcoming chemotherapy resistance in low-grade gliomas: A computational approach
Delobel T, Ayala-Hernández LE, Bosque JJ, Pérez-Beteta J, Chulián S, García-Ferrer M, Piñero P, Schucht P, Murek M, Pérez-García VM
PLoS Computational Biology 19(11): e1011208 (2023)
Radiation necrosis after radiation therapy treatment of brain metastases: A computational approach
Beatriz Ocana-Tienda, Odelaisy Leon-Triana, Julian Perez-Beteta, Juan Jiménez-Sánchez, Victor M. Perez-Garcia
PLOS Computational Biology 20(1) e1011400 (2024)
Stochastic Fluctuations Drive Non-genetic Evolution of Proliferation in Clonal Cancer Cell Populations
C Ortega-Sabater, GF Calvo, Jelena Dinic, Ana Podolski, Milica Pesic, VM Perez-Garcia
Bulletin of Mathematical Biology 85(1) 8 (2023)
The local microenvironment drives activation of neutrophils in human brain tumors
Maas RR, Soukup K, Fournier N, Massara M, Galland S, Kornete M, Wischnewski V, Lourenco J, Croci D, Álvarez-Prado ÁF, Marie DN, Lilja J, Marcone R, Calvo GF, Santalla Mendez R, Aubel P, Bejarano L, Wirapati P, Ballesteros I, Hidalgo A, Hottinger AF, Brouland JP, Daniel RT, Hegi ME, Joyce JA
Cell 186, 1-21 (2023)
The shape of cancer relapse: Topological data analysis predicts recurrence in paediatric acute lymphoblastic leukaemia
S. Chulián, B. J. Stolz, A. Martínez-Rubio, C. Blázquez-Goñi, J. F. Rodríguez, T. Caballero, A. Molinos, M. Ramírez-Orellana, A. Castillo, J. L. Fuster, A. Minguela, M. V. Martínez, M. Rosa, V. M. Pérez-García, H. Byrne
PLOS Computational Biology 19(8) e1011329 (2023)
Variable selection for dimensionality reduction of biological datasets through bootstrapping of correlation networks
D.G. Aragones, M. Palomino, J. Sicilia, G. Crainiciuc, I. Ballesteros, F. Sánchez-Cabo, A. Hidalgo, G.F. Calvo
Computers in Biology and Medicine 168, 107827 (2024).
Volumetric Analysis: Rethinking Brain Metastases Response Assessment
B Ocaña-Tienda, J Pérez-Beteta, JA Romero-Rosales, B Asenjo, A Ortiz, LA Pérez Romasanta, JD Albillo, F Nagib, M Vidal Denis, B. Luque, E. Arana, VM Pérez-García
Neuro-Oncoloy Advances 6(1), 1-9 (2024)
A glance at evolvability: a theoretical analysis of its role in the evolutionary dynamics of cell populations
J. Jiménez-Sánchez, C. Ortega-Sabater, P. K. Maini, V.M. Pérez-García, T. Lorenzi
arXiv:2402.06392
A mathematical model for fibrous dysplasia: The role of the flow of mutant cells
M Soloviova, JC Beltran Vargas, L Fernandez de Castro, J Belmonte-Beitia, VM Pérez-García, M Caballero
arXiv:2402.07724 (2024)
Breaking Down Cell-Free DNA Fragmentation: A Markov Model Approach
Terence H.L. Tsui, Phil F. Xie, Salvador Chulián, Víctor M. Pérez-García
biorxiv (doi:10.1101/2023.07.06.547953)
Understanding the role of B-cells in CART-cell therapy in leukemia through a mathematical model
Sergio Serrano, Roberto Barrio, Alvaro Martinez-Rubio, Juan Belmonte-Beitiia, Victor M. Perez-Garcia
arXiv.org/2403.00340