Publications

A comprehensive dataset of annotated brain metastasis MR images with clinical and radiomic data

Ocaña-Tienda B, Pérez-Beteta J, Villanueva JD, Romero JA, Molina D, Suter Y, Asenjo B, Albillo D, Ortiz A, Pérez-Romasanta LA, González E, Llorente M, Carballo N, Nagib F, Vidal M, Luque B, Reyes M, Arana E, Pérez-García VM

Scientific Data 10, 208 (2023)

A Mathematical Model for Fibrous Dysplasia: The Role of the Flow of Mutant Cells

M. Soloviova, J.C. Beltrán-Vargas, L. Fernández De Castro, J. Belmonte-Beitia, V.M. Pérez-García, M. Caballero

Bulletin of Mathematical Biology 86, 108 (2024)

Analytical performance validation of aPROMISE platform for prostate tumor burden

García Vicente, A.M., Lucas Lucas, C., Pérez-Beteta, J. et al.

Scientific Reports 14, 3001 (2024)

Asymptotic dynamics and optimal treatment for a model of tumour resistance to chemotherapy

Mariusz Bodzioch, Juan Belmonte-Beitia, Urszula Forys

Applied Mathematical Modelling, 135 (2024), 620-639

Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression

O Molina, C Ortega-Sabater, N Thampi, N Fernández, M Guerrero, A Martínez, M Vinyoles, T Velasco, C Bueno, JL Trincado, I Granada, D Campos, C Giménez, JM Boer , ML den Boer, GF Calvo, Mireia Camós, JL Fuster P Velasco, P Ballerini, F Locatelli, CG Mullighan, DCJ Spierings, F Foijer, VM Pérez-García, P Menéndez

EMBO Molecular Medicine 16, 64-92 (2024)

Deterministic reprogramming of neutrophils within tumors

M.S.F. Ng, I. Kwok, L. Tan, C. Shi, D. Cerezo, Y. Tan, K. Leong, G.F. Calvo, K. Yang, Y. Zhang, J. Jin, K.H. Liong, D. Wu, R. He, ..., A. Hidalgo, F. Ginhoux, L.G. Ng

Science 383, eadf6493 (2024)

Growth dynamics of brain metastases differentiate radiation necrosis from recurrence

B. Ocaña-Tienda, J. Pérez-Beteta, D. Molina-García, B. Asenjo, A. Ortiz de Mendivil, D. Albillo, LA Pérez-Romasanta, E. González del Portillo, M. Llorente, N. Carballo, E. Arana, Víctor M Pérez-García

Neurooncology Advances 5(1), vdac179 (2023)

Growth dynamics of lung nodules: implications for classification in lung cancer screening

B. Ocaña-Tienda, A. Eroles-Simó, J. Pérez-Beteta, E. Arana, V. M. Pérez-García

Cancer Imaging 24, 113 (2024)

Growth exponents reflect evolutionary processes and treatment response in brain metastases

B. Ocaña-Tienda, J. Pérez-Beteta, D. Molina-García, J. Jiménez-Sánchez, O. Leon-Triana, A. Ortiz de Mendivil, B. Asenjo, D. Albillo, L. Pérez-Romasanta, M. Valiente, L. Zhu, P. García- Gómez, E. González-Del Portillo, M. Llorente, N. Carballo, E. Arana, V. M. Pérez-García

npj Systems Biology and Applications 9, 35 (2023)

Integrated modeling of labile and glycated hemoglobin with glucose for enhanced diabetes detection and short-term monitoring

Romero-Rosales JA, Aragones DG, Escribano-Serrano J, Borrachero MG, Doña AM, Macías López FJ, Santos Mata MA, Jiménez IN, Casamitjana Zamora MJ, Serrano H, Belmonte-Beitia J, Durán MR, Calvo GF

iScience. 27(4), 109369 (2024)

Mathematical modeling of brain metastases growth and response to therapies: A review

Beatriz Ocaña-Tienda, Víctor M. Pérez-García

Mathematical Biosciences 373, 109207 (2024)

Mathematical Modeling of Leukemia Chemotherapy in Bone Marrow

Ana Niño-López, Salvador Chulián, Álvaro Martínez-Rubio, Cristina Blázquez-Goñi, María Rosa

Mathematical Modelling of Natural Phenomena 18, 21 (2023)

Mean first-passage time of cell migration in confined domains

H. Serrano, R.F. Álvarez-Estrada, G.F. Calvo

Mathematical Methods in the Applied Sciences 46, 7435-7453 (2023)

Metabolic Activity Grows in Human Cancers Pushed by Phenotypic Variability

J.J. Bosque, G.F. Calvo, D. Molina-García, J. Pérez-Beteta, A.M. García Vicente, V. M. Pérez-García

iScience 26(3) 106118 (2023)

Morphological MRI features as prognostic indicators in brain metastases

Ocaña-Tienda B, Pérez-Beteta J, Ortiz de Mendivil A, Asenjo B, Albillo D, Pérez-Romasanta LA, LLorente M, Carballo N, Arana E, Pérez-García VM.

Cancer Imaging 24, 111 (2024)

On the Analysis of a Mathematical Model of CAR-T Cell Therapy for Glioblastoma: Insights from a Mathematical Model

Bodnar, M ; Forys, U ; Piotrowska, MJ ; Bodzioch, M ; Romero-Rosales, JA; Belmonte-Beitia, J

International Journal of Applied Mathematics and Computer Science 33(3), 379-394 (2023)

On the Dynamics and Optimal Control of a Mathematical Model of Neuroblastoma and its Treatment: Insights from a Mathematical Model

José García Otero, Mariusz Bodzioch, and Juan Belmonte-Beitia

M3AS: Mathematical Models and Methods in Applied Sciences 07(34) (2024)

Overcoming chemotherapy resistance in low-grade gliomas: A computational approach

Delobel T, Ayala-Hernández LE, Bosque JJ, Pérez-Beteta J, Chulián S, García-Ferrer M, Piñero P, Schucht P, Murek M, Pérez-García VM

PLoS Computational Biology 19(11): e1011208 (2023)

Radiation necrosis after radiation therapy treatment of brain metastases: A computational approach

Beatriz Ocana-Tienda, Odelaisy Leon-Triana, Julian Perez-Beteta, Juan Jiménez-Sánchez, Victor M. Perez-Garcia

PLOS Computational Biology 20(1) e1011400 (2024)

Stochastic Fluctuations Drive Non-genetic Evolution of Proliferation in Clonal Cancer Cell Populations

C Ortega-Sabater, GF Calvo, Jelena Dinic, Ana Podolski, Milica Pesic, VM Perez-Garcia

Bulletin of Mathematical Biology 85(1) 8 (2023)

The local microenvironment drives activation of neutrophils in human brain tumors

Maas RR, Soukup K, Fournier N, Massara M, Galland S, Kornete M, Wischnewski V, Lourenco J, Croci D, Álvarez-Prado ÁF, Marie DN, Lilja J, Marcone R, Calvo GF, Santalla Mendez R, Aubel P, Bejarano L, Wirapati P, Ballesteros I, Hidalgo A, Hottinger AF, Brouland JP, Daniel RT, Hegi ME, Joyce JA

Cell 186, 1-21 (2023)

The shape of cancer relapse: Topological data analysis predicts recurrence in paediatric acute lymphoblastic leukaemia

S. Chulián, B. J. Stolz, A. Martínez-Rubio, C. Blázquez-Goñi, J. F. Rodríguez, T. Caballero, A. Molinos, M. Ramírez-Orellana, A. Castillo, J. L. Fuster, A. Minguela, M. V. Martínez, M. Rosa, V. M. Pérez-García, H. Byrne

PLOS Computational Biology 19(8) e1011329 (2023)

Understanding the role of B cells in CAR T-cell therapy in leukemia through a mathematical model

S. Serrano, R. Barrio, A. Martínez-Rubio, J. Belmonte-Beitia, V. M. Pérez-García

Chaos 34, 083142 (2024)

Variable selection for dimensionality reduction of biological datasets through bootstrapping of correlation networks

D.G. Aragones, M. Palomino, J. Sicilia, G. Crainiciuc, I. Ballesteros, F. Sánchez-Cabo, A. Hidalgo, G.F. Calvo

Computers in Biology and Medicine 168, 107827 (2024).

Volumetric Analysis: Rethinking Brain Metastases Response Assessment

B Ocaña-Tienda, J Pérez-Beteta, JA Romero-Rosales, B Asenjo, A Ortiz, LA Pérez Romasanta, JD Albillo, F Nagib, M Vidal Denis, B. Luque, E. Arana, VM Pérez-García

Neuro-Oncoloy Advances 6(1), 1-9 (2024)