Andrés Méndiz Fernández has presented his Master’s Final Project, titled “In silico analysis of intermittent fasting schemes using mathematical models of glucose homeostasis.”

The work develops a quantitative framework to study how meal timing affects systemic energy availability. It combines:

1. A differential-equation model of glucose–insulin–glucagon dynamics with analytical characterization of steady states and stability.

2. Simulations of intermittent fasting regimes, keeping total daily intake constant and introducing periodic feeding windows.

The model shows how compressing eating periods or incorporating fasting days shifts glucose and hormone dynamics and modulates hepatic reserves, helping identify physiologically viable fasting patterns.

This study provides mechanistic criteria to guide non-pharmacological metabolic interventions and sets the basis for future coupling with tumor growth models to analyze resource-limitation effects in cancer.

Congratulations to Andrés for his excellent work and looking forward to new progresses in the context of his PhD.