Mathematical modeling for the improvement of cellular immunotherapies and radiopharmaceutical treatments.
Our goal is to develop mechanistic digital twins that simulate the response to advanced therapies and optimize their clinical application in two areas of high current relevance: radiopharmaceuticals and CAR T-cell immunotherapies. Although these therapies differ in their clinical administration, they share common challenges from a mathematical modeling perspective, such as predicting efficacy, characterizing toxicity, and understanding the emergence of resistance.
Funding entity
Partially supported by University of Castilla-La Mancha / ERDF, A way of making Europe (Applied Research Projects) under grant 2025-GRIN-38309 (2025-2028)
Principal investigator