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BSc in Mathematics (Universidad de Cádiz, 2016). MSc in Mathematics (Universidad de Cádiz, 2018). PhD in Mathematics (2022) at Universidad de Castilla-La Mancha. His activity focuses on the development of mathematical models and data analysis in childhood Acute Lymphoblastic Leukemia (ALL). |
Publications
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Breaking Down Cell-Free DNA Fragmentation: A Markov Model Approach
biorxiv (doi:10.1101/2023.07.06.547953)
Terence H.L. Tsui, Phil F. Xie, Salvador Chulián, Víctor M. Pérez-García -
Mathematical Modeling of Leukemia Chemotherapy in Bone Marrow
Mathematical Modelling of Natural Phenomena 18, 21 (2023)
Ana Niño-López, Salvador Chulián, Álvaro Martínez-Rubio, Cristina Blázquez-Goñi, María Rosa -
Overcoming chemotherapy resistance in low-grade gliomas: A computational approach
PLoS Computational Biology 19(11): e1011208 (2023)
Delobel T, Ayala-Hernández LE, Bosque JJ, Pérez-Beteta J, Chulián S, García-Ferrer M, Piñero P, Schucht P, Murek M, Pérez-García VM -
The shape of cancer relapse: Topological data analysis predicts recurrence in paediatric acute lymphoblastic leukaemia
PLOS Computational Biology 19(8) e1011329 (2023)
S. Chulián, B. J. Stolz, A. Martínez-Rubio, C. Blázquez-Goñi, J. F. Rodríguez, T. Caballero, A. Molinos, M. Ramírez-Orellana, A. Castillo, J. L. Fuster, A. Minguela, M. V. Martínez, M. Rosa, V. M. Pérez-García, H. Byrne -
Mathematical models of leukaemia and its treatment: a review
SEMA Journal 79, 441-486 (2022)
S. Chulián, Á. Martínez-Rubio, M. Rosa, V. M. Pérez-García -
A Mathematical Description of the Bone Marrow Dynamics of CAR T-Cell Therapy in B-cell Childhood Acute Lymphoblastic Leukemia
International J. of Molecular Sciences 22, 6371 (2021)
A. Martínez-Rubio, S. Chulián, C. Blázquez Goñi, A. Pérez Martínez, M. Ramírez Orellana, A. Navarro-Zapata, C. Ferreras, V.M. Pérez-García, M. Rosa -
CAR T cell therapy in B-cell acute lymphoblastic leukaemia: Insights from mathematical models
Comm Nonlin Sci Numer Simul 94, 105570 (2021)
O. León-Triana, S. Sabir, G.F. Calvo, J. Belmonte-Beitia, S. Chulian, A. Martínez-Rubio, M. Rosa, A. Pérez-Martínez, M. Ramírez-Orellana, V.M. Pérez-García -
Dynamical properties of feedback signalling in B lymphopoiesis: A mathematical modelling approach
Journal of Theoretical Biology 110685 (2021)
S. Chulián, A. Martínez-Rubio, A. Marciniak-Czochra, T. Stiehl, C.B. Goñi, J.F. Rodríguez Gutiérrez, M.R. Orellana, A.C. Robleda, V.M. Pérez-García, M. Rosa -
High-dimensional Analysis of Single-cell Flow Cytometry Data Predicts Relapse in Childhood Acute Lymphoblastic Leukemia
Cancers 13(1), 17 (2021).
S. Chulián, A. Martínez-Rubio, V.M. Pérez-García, M. Rosa, C. Blázquez-Goñi, J.F. Rodríguez Gutiérrez, L. Hermosín-Ramos, A. Molinos-Quintana, T. Caballero-Velázquez, M. Ramírez-Orellana, A. Castillo Robleda, J.L Fernández-Martínez
Projects
- Mathematical models for the digital transition in neuro-oncology: In-silico design of a clinical trial for glioblastoma.
Ministerio de Ciencia e Innovación (NextGenerationEU) (2023 - 2024) - Mathematics applied to pediatric oncohematology
Ministry of Science and Innovation (National Research Plan) (2023 - 2026) - Validation and transfer of oncological data and biomarkers based on mathematical models (AFTERbioMATH)
Ministry of Science and Innovation (Spain), Proof of Concept Program (2023 - 2024) - Early identification of relapse and treatment optimization in acute lymphoblastic leukaemias through mathematical modelling and discriminant analysis
Junta de Andalucía (2020 - 2023) - Improving cell therapies in neuroblastoma through mathematical modelling
NeN Association (2020 - 2023) - Mathematical models in Oncology
Ministerio de Ciencia e Innovación (Spain) (2020 - 2023)
Chulián García, Salvador
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BSc in Mathematics (Universidad de Cádiz, 2016). MSc in Mathematics (Universidad de Cádiz, 2018). PhD in Mathematics (2022) at Universidad de Castilla-La Mancha. His activity focuses on the development of mathematical models and data analysis in childhood Acute Lymphoblastic Leukemia (ALL). |
Publications
- Breaking Down Cell-Free DNA Fragmentation: A Markov Model Approach
biorxiv (doi:10.1101/2023.07.06.547953)
Terence H.L. Tsui, Phil F. Xie, Salvador Chulián, Víctor M. Pérez-García - Mathematical Modeling of Leukemia Chemotherapy in Bone Marrow
Mathematical Modelling of Natural Phenomena 18, 21 (2023)
Ana Niño-López, Salvador Chulián, Álvaro Martínez-Rubio, Cristina Blázquez-Goñi, María Rosa - Overcoming chemotherapy resistance in low-grade gliomas: A computational approach
PLoS Computational Biology 19(11): e1011208 (2023)
Delobel T, Ayala-Hernández LE, Bosque JJ, Pérez-Beteta J, Chulián S, García-Ferrer M, Piñero P, Schucht P, Murek M, Pérez-García VM - The shape of cancer relapse: Topological data analysis predicts recurrence in paediatric acute lymphoblastic leukaemia
PLOS Computational Biology 19(8) e1011329 (2023)
S. Chulián, B. J. Stolz, A. Martínez-Rubio, C. Blázquez-Goñi, J. F. Rodríguez, T. Caballero, A. Molinos, M. Ramírez-Orellana, A. Castillo, J. L. Fuster, A. Minguela, M. V. Martínez, M. Rosa, V. M. Pérez-García, H. Byrne - Mathematical models of leukaemia and its treatment: a review
SEMA Journal 79, 441-486 (2022)
S. Chulián, Á. Martínez-Rubio, M. Rosa, V. M. Pérez-García - A Mathematical Description of the Bone Marrow Dynamics of CAR T-Cell Therapy in B-cell Childhood Acute Lymphoblastic Leukemia
International J. of Molecular Sciences 22, 6371 (2021)
A. Martínez-Rubio, S. Chulián, C. Blázquez Goñi, A. Pérez Martínez, M. Ramírez Orellana, A. Navarro-Zapata, C. Ferreras, V.M. Pérez-García, M. Rosa - CAR T cell therapy in B-cell acute lymphoblastic leukaemia: Insights from mathematical models
Comm Nonlin Sci Numer Simul 94, 105570 (2021)
O. León-Triana, S. Sabir, G.F. Calvo, J. Belmonte-Beitia, S. Chulian, A. Martínez-Rubio, M. Rosa, A. Pérez-Martínez, M. Ramírez-Orellana, V.M. Pérez-García - Dynamical properties of feedback signalling in B lymphopoiesis: A mathematical modelling approach
Journal of Theoretical Biology 110685 (2021)
S. Chulián, A. Martínez-Rubio, A. Marciniak-Czochra, T. Stiehl, C.B. Goñi, J.F. Rodríguez Gutiérrez, M.R. Orellana, A.C. Robleda, V.M. Pérez-García, M. Rosa - High-dimensional Analysis of Single-cell Flow Cytometry Data Predicts Relapse in Childhood Acute Lymphoblastic Leukemia
Cancers 13(1), 17 (2021).
S. Chulián, A. Martínez-Rubio, V.M. Pérez-García, M. Rosa, C. Blázquez-Goñi, J.F. Rodríguez Gutiérrez, L. Hermosín-Ramos, A. Molinos-Quintana, T. Caballero-Velázquez, M. Ramírez-Orellana, A. Castillo Robleda, J.L Fernández-Martínez
Projects
- Mathematical models for the digital transition in neuro-oncology: In-silico design of a clinical trial for glioblastoma.
Ministerio de Ciencia e Innovación (NextGenerationEU) (2023 - 2024) - Mathematics applied to pediatric oncohematology
Ministry of Science and Innovation (National Research Plan) (2023 - 2026) - Validation and transfer of oncological data and biomarkers based on mathematical models (AFTERbioMATH)
Ministry of Science and Innovation (Spain), Proof of Concept Program (2023 - 2024) - Early identification of relapse and treatment optimization in acute lymphoblastic leukaemias through mathematical modelling and discriminant analysis
Junta de Andalucía (2020 - 2023) - Improving cell therapies in neuroblastoma through mathematical modelling
NeN Association (2020 - 2023) - Mathematical models in Oncology
Ministerio de Ciencia e Innovación (Spain) (2020 - 2023)
