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“Graduate (1991) PhD (Complutense U., Madrid, 1995). Associate professor (1997) and full professor (2002) in Applied Mathematics at the Mathematics Department of the University of Castilla-La Mancha. He has published more than 170 research papers with more than 11000 Google citations and has an H-index of 52. He is editor in chief of the journal “Physica D: “Nonlinear Phenomena” and serves in the editorial board of “npj Systems Biology and Applications”. He is the coordinator of the Applied Mathematics panel at the Spanish National Research Agency and has been a member of the Marie Curie evaluation committee and of many international project evaluation boards in oncology and/or applied mathematics in France, UK, Poland, Austria, Romania, Cyprus, Latvia, Spain, etc. His main field of research is the application of mathematical modeling to oncology and more specifically to brain tumors, metastasis, cellular immunotherapies, biomarkers, medical images, lymphomas, leukaemias, prostate cancer, etc. In this field he has led several projects funded by public institutions, private foundations such as the James S. Mc. Donnell Foundation and pharmaceutical companies such as NOVARTIS. More specifically he is interested in the development and validation of mechanistic mathematical models that shed light on oncological processes and may be used as platforms to personalize treatments and develop in-silico trials. Also he is interested in the development of mathematical model-based biomarkers of response to treatments.” |
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Identification of a transient state during the acquisition of temozolomide resistance in glioblastoma
Cell Death & Disease 11, 19 (2020)
M. Rabe, S. Dummont, A. Álvarez-Arenas Alcami, H. Janati, J. Belmonte-Beitia, G.F. Calvo, C. Thibault-Charpentier, Q. Séry, C. Chauvin, N. Joalland, F. Briand, E. Scotet, C. Pecqueur, J. Clairambault, L. Oliver, A. Nadaradjane, V.M. Pérez-García, P. François Cartron, C. Gratas, F.M. Vallette -
Mitochondria transfer from tumor-activated stromal cells (TASCs) to primary Glioblastoma cells.
Biochemical and Biophysical Research Communications 533(1) 139-147 (2020)
C. Salaud, A. Alvarez-Arenas Alcami, F. Geraldo, J. Belmonte-Beitia, G.F. Calvo, C. Gratas, C. Pecqueur, D. Garnier, V.M. Pérez- García, F.M. Vallette, L. Oliver -
Relaxing quarantine after an epidemic: A mathematical study of the Spanish COVID-19 case
Researchgate preprint doi:10.13140/RG.2.2.36674.73929/1
V.M. Pérez-García -
Tumor width on T1-weighted MRI images of glioblastoma as a prognostic biomarker: A mathematical model
Mathematical Modelling of Natural Phenomena 15, 10 (2020)
J. Pérez Beteta, J. Belmonte-Beitia, V.M. Pérez-García -
Universal scaling laws rule explosive growth in human cancers
Nature Physics 16, 1232-1237 (2020)
V.M. Pérez-García, G.F. Calvo, J.J. Bosque, O. León-Triana, J. Jiménez-Sánchez, J. Pérez-Beteta, J. Belmonte-Beitia, M. Valiente, L. Zhu, P. García-Gómez, P. Sánchez-Gómez, E. Hernández, R. Hortigüela, Y. Azimzade, D. Molina-García, A.Martínez-Rubio, A. Acosta, A. Ortiz de Mendivil, F. Vallette, P. Schucht, M. Murek, M.Pérez-Cano, D.Albillo, AF Honguero, G.A. Jiménez, E. Arana, AM García-Vicente -
Universal scaling laws rule explosive growth in human cancers
Nature Physics 16, 1232-1237 (2020)
V.M. Pérez-García, G.F. Calvo, J.J. Bosque, O. León-Triana, J. Jiménez-Sánchez, J. Pérez-Beteta, J. Belmonte-Beitia, M. Valiente, L. Zhu, P. García-Gómez, P. Sánchez-Gómez, E. Hernández, R. Hortigüela, Y. Azimzade, D. Molina-García, A.Martínez-Rubio, A. Acosta, A. Ortiz de Mendivil, F. Vallette, P. Schucht, M. Murek, M.Pérez-Cano, D.Albillo, AF Honguero, G.A. Jiménez, E. Arana, AM García-Vicente
- Mathematical modeling for the improvement of cellular immunotherapies and radiopharmaceutical treatments.
Partially supported by University of Castilla-La Mancha / ERDF, A way of making Europe (Applied Research Projects) under grant 2025-GRIN-38309 (2025 - 2028) - Model-based digital twins for biomarker development and virtual clinical trials in oncology.
Supported by project SBPLY/24/180225/000193, funded by Junta de Comunidades de Castilla-La Mancha. Spain and European Regional Development Fund (ERDF A way of making Europe). (2025 - 2028) - Establishing a non-invasive approach to accurately diagnose and assess brain tumors
Canadian Cancer Society (2024 - 2027) - Improving New Therapies in Oncology and Related Fields using mathematical models and biomedical data
Ministry of Science and Innovation (National Research Plan) (2023 - 2026) - Mathematical models for the digital transition in neuro-oncology: In-silico design of a clinical trial for glioblastoma.
Ministerio de Ciencia e Innovación (NextGenerationEU) (2023 - 2024) - Optimization of tisagenlecleucel treatments of lymphoma: An integrated human data-based approach using mathematical models
NOVARTIS (2023 - 2025) - Validation and transfer of oncological data and biomarkers based on mathematical models (AFTERbioMATH)
Ministry of Science and Innovation (Spain), Proof of Concept Program (2023 - 2024)
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“Graduate (1991) PhD (Complutense U., Madrid, 1995). Associate professor (1997) and full professor (2002) in Applied Mathematics at the Mathematics Department of the University of Castilla-La Mancha. He has published more than 170 research papers with more than 11000 Google citations and has an H-index of 52. He is editor in chief of the journal “Physica D: “Nonlinear Phenomena” and serves in the editorial board of “npj Systems Biology and Applications”. He is the coordinator of the Applied Mathematics panel at the Spanish National Research Agency and has been a member of the Marie Curie evaluation committee and of many international project evaluation boards in oncology and/or applied mathematics in France, UK, Poland, Austria, Romania, Cyprus, Latvia, Spain, etc. His main field of research is the application of mathematical modeling to oncology and more specifically to brain tumors, metastasis, cellular immunotherapies, biomarkers, medical images, lymphomas, leukaemias, prostate cancer, etc. In this field he has led several projects funded by public institutions, private foundations such as the James S. Mc. Donnell Foundation and pharmaceutical companies such as NOVARTIS. More specifically he is interested in the development and validation of mechanistic mathematical models that shed light on oncological processes and may be used as platforms to personalize treatments and develop in-silico trials. Also he is interested in the development of mathematical model-based biomarkers of response to treatments.” |
- Identification of a transient state during the acquisition of temozolomide resistance in glioblastoma
Cell Death & Disease 11, 19 (2020)
M. Rabe, S. Dummont, A. Álvarez-Arenas Alcami, H. Janati, J. Belmonte-Beitia, G.F. Calvo, C. Thibault-Charpentier, Q. Séry, C. Chauvin, N. Joalland, F. Briand, E. Scotet, C. Pecqueur, J. Clairambault, L. Oliver, A. Nadaradjane, V.M. Pérez-García, P. François Cartron, C. Gratas, F.M. Vallette - Mitochondria transfer from tumor-activated stromal cells (TASCs) to primary Glioblastoma cells.
Biochemical and Biophysical Research Communications 533(1) 139-147 (2020)
C. Salaud, A. Alvarez-Arenas Alcami, F. Geraldo, J. Belmonte-Beitia, G.F. Calvo, C. Gratas, C. Pecqueur, D. Garnier, V.M. Pérez- García, F.M. Vallette, L. Oliver - Relaxing quarantine after an epidemic: A mathematical study of the Spanish COVID-19 case
Researchgate preprint doi:10.13140/RG.2.2.36674.73929/1
V.M. Pérez-García - Tumor width on T1-weighted MRI images of glioblastoma as a prognostic biomarker: A mathematical model
Mathematical Modelling of Natural Phenomena 15, 10 (2020)
J. Pérez Beteta, J. Belmonte-Beitia, V.M. Pérez-García - Universal scaling laws rule explosive growth in human cancers
Nature Physics 16, 1232-1237 (2020)
V.M. Pérez-García, G.F. Calvo, J.J. Bosque, O. León-Triana, J. Jiménez-Sánchez, J. Pérez-Beteta, J. Belmonte-Beitia, M. Valiente, L. Zhu, P. García-Gómez, P. Sánchez-Gómez, E. Hernández, R. Hortigüela, Y. Azimzade, D. Molina-García, A.Martínez-Rubio, A. Acosta, A. Ortiz de Mendivil, F. Vallette, P. Schucht, M. Murek, M.Pérez-Cano, D.Albillo, AF Honguero, G.A. Jiménez, E. Arana, AM García-Vicente - Universal scaling laws rule explosive growth in human cancers
Nature Physics 16, 1232-1237 (2020)
V.M. Pérez-García, G.F. Calvo, J.J. Bosque, O. León-Triana, J. Jiménez-Sánchez, J. Pérez-Beteta, J. Belmonte-Beitia, M. Valiente, L. Zhu, P. García-Gómez, P. Sánchez-Gómez, E. Hernández, R. Hortigüela, Y. Azimzade, D. Molina-García, A.Martínez-Rubio, A. Acosta, A. Ortiz de Mendivil, F. Vallette, P. Schucht, M. Murek, M.Pérez-Cano, D.Albillo, AF Honguero, G.A. Jiménez, E. Arana, AM García-Vicente
- Mathematical modeling for the improvement of cellular immunotherapies and radiopharmaceutical treatments.
Partially supported by University of Castilla-La Mancha / ERDF, A way of making Europe (Applied Research Projects) under grant 2025-GRIN-38309 (2025 - 2028) - Model-based digital twins for biomarker development and virtual clinical trials in oncology.
Supported by project SBPLY/24/180225/000193, funded by Junta de Comunidades de Castilla-La Mancha. Spain and European Regional Development Fund (ERDF A way of making Europe). (2025 - 2028) - Establishing a non-invasive approach to accurately diagnose and assess brain tumors
Canadian Cancer Society (2024 - 2027) - Improving New Therapies in Oncology and Related Fields using mathematical models and biomedical data
Ministry of Science and Innovation (National Research Plan) (2023 - 2026) - Mathematical models for the digital transition in neuro-oncology: In-silico design of a clinical trial for glioblastoma.
Ministerio de Ciencia e Innovación (NextGenerationEU) (2023 - 2024) - Optimization of tisagenlecleucel treatments of lymphoma: An integrated human data-based approach using mathematical models
NOVARTIS (2023 - 2025) - Validation and transfer of oncological data and biomarkers based on mathematical models (AFTERbioMATH)
Ministry of Science and Innovation (Spain), Proof of Concept Program (2023 - 2024)