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Graduate (1991) PhD (Complutense U., Madrid, 1995). Associate professor (1997) and full professor (2002) in Applied Mathematics at the Mathematics Department of the University of Castilla-La Mancha. Founding (2007-2012) and current (2016-) director of the Institute of Applied Mathematics in Science and Engineering (UCLM). Director of the department of mathematics (2005-2008, 2012-2016) at the same university. He has published more than 170 ISI-indexed research papers with 5800 citations and has an H-index of 40 (web of Science). He is editor in chief of "Physica D" and serves in the editorial boards of "Cancers", "European Radiology" and other journals. He is a member of the scientific committees of the Spanish Royal Society of Mathematics, the board of "Mathematical Action against coronavirus". He is a manager of Applied Mathematics at the Spanish National Research Agency. He has been a member of the Marie Curie evaluation committee and of many international project evaluation boards in oncology and/or applied mathematics in France, UK, Poland, Austria, Romania, Cyprus, Latvia, Spain, etc.
His main field of research is the application of mathematical modeling to oncology and more specifically to brain tumors, metastasis, cellular immunotherapies, biomarkers, medical images, lymphomas, leukaemias, prostate cancer, etc. In this field he leads several projects funded by public institutions, private foundations such as the James S. Mc. Donnell Foundation and pharmaceutical companies such as NOVARTIS. |
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Evolutionary dynamics at the tumor edge reveals metabolic imaging biomarkers
Proceedings of the National Academy of Sciences (USA) 118(6) e2018110118 (2021).
J. Jiménez-Sánchez, J.J. Bosque, G.A. Jiménez-Londoño, D. Molina-García, A. Martínez-Rubio, J. Pérez-Beteta, C. Ortega-Sabater, A.F Honguero-Martínez, A.M. García-Vicente, G.F. Calvo, V.M. Pérez-García -
A Mathematical Description of the Bone Marrow Dynamics of CAR T-Cell Therapy in B-cell Childhood Acute Lymphoblastic Leukemia
International J. of Molecular Sciences 22, 6371 (2021)
A. Martínez-Rubio, S. Chulián, C. Blázquez Goñi, A. Pérez Martínez, M. Ramírez Orellana, A. Navarro-Zapata, C. Ferreras, V.M. Pérez-García, M. Rosa -
A mesoscopic simulator to uncover heterogeneity and evolutionary dynamics in tumors
PLoS Computational Biology 17(2) e1008266 (2021).
J. Jiménez-Sánchez, A. Martínez-Rubio, A. Popov, J. Pérez-Beteta, Y. Azimzade, D. Molina-García, J. Belmonte-Beitia, G.F. Calvo, V.M. Pérez-García -
Brain Metastasis Response to Stereotactic Radio Surgery: A Mathematical Approach
Mathematics 9(7) 716 (2021)
O. León-Triana, J. Pérez-Beteta, D. Albillo, A. Ortiz de Mendivil, L.A. Pérez-Romasanta, E. González del Portillo, M. Llorente, N. Carballo, E. Arana, V.M. Pérez-García -
CAR T cell therapy in B-cell acute lymphoblastic leukaemia: Insights from mathematical models
Comm Nonlin Sci Numer Simul 94, 105570 (2021)
O. León-Triana, S. Sabir, G.F. Calvo, J. Belmonte-Beitia, S. Chulian, A. Martínez-Rubio, M. Rosa, A. Pérez-Martínez, M. Ramírez-Orellana, V.M. Pérez-García -
CAR T cells for T-cell leukemias: Insights from mathematical models
Comm Nonlin Sci Numer Simul, 96, 105684 (2021)
V.M. Pérez-García, O. León-Triana, M. Rosa, A. Pérez-Martínez -
Dual-Target Car-Ts With on- and off-Tumour Activity May Override Immune Suppression in Solid Cancers: A Mathematical Proof of Concept
Cancers 13, 703 (2021)
O. León-Triana, A. Pérez-Martínez, M. Ramírez-Orellana, V.M. Pérez-García -
Dynamical properties of feedback signalling in B lymphopoiesis: A mathematical modelling approach
Journal of Theoretical Biology 110685 (2021)
S. Chulián, A. Martínez-Rubio, A. Marciniak-Czochra, T. Stiehl, C.B. Goñi, J.F. Rodríguez Gutiérrez, M.R. Orellana, A.C. Robleda, V.M. Pérez-García, M. Rosa -
High-dimensional Analysis of Single-cell Flow Cytometry Data Predicts Relapse in Childhood Acute Lymphoblastic Leukemia
Cancers 13(1), 17 (2021).
S. Chulián, A. Martínez-Rubio, V.M. Pérez-García, M. Rosa, C. Blázquez-Goñi, J.F. Rodríguez Gutiérrez, L. Hermosín-Ramos, A. Molinos-Quintana, T. Caballero-Velázquez, M. Ramírez-Orellana, A. Castillo Robleda, J.L Fernández-Martínez -
In vitro biomimetic models for glioblastoma-a promising tool for drug response studies
Drug Resistance Updates 55, 100753 (2021)
T. Stankovic, T. Randelovic, M. Dragoj, S.S. Buric, L. Fernández, I. Ochoa, V.M. Pérez-García, M. Pesic -
Nonlinear science against the COVID-19 pandemic
Physica D 424 (2021) 132946
V.M. Pérez-García -
Optimal Combinations of Chemotherapy and Radiotherapy in Low-Grade Gliomas: A Mathematical Approach
Journal of Personalized Medicine 2021, 11 (2021) 1036
L. E. Ayala-Hernández, A. Gallegos, P. Schucht, M. Murek, L. A. Pérez-Romasanta, J. Belmonte-Beitia, V. M. Pérez-García -
The interplay of blood flow and temperature in regional hyperthermia: a mathematical approach
Royal Society Open Science 8, 201234 (2021)
J.J. Bosque, G.F. Calvo, V.M Pérez-García, M.C. Navarro
- Early identification of relapse and treatment optimization in acute lymphoblastic leukaemias through mathematical modelling and discriminant analysis
Junta de Andalucía (2020 - 2023) - Improving cell therapies in neuroblastoma through mathematical modelling
NeN Association (2020 - 2023) - Mathematical models in Oncology
Ministerio de Ciencia e Innovación (Spain) (2020 - 2023) - Mathematical models of tumor growth and response to therapies
Junta de Comunidades de Castilla-La Mancha (2018 - 2021) - Therapy Optimization in Glioblastoma: An integrative human data-based approach using mathematical models (Stage II)
James S. Mc. Donnell Foundation (USA) (2018 - 2021)

Graduate (1991) PhD (Complutense U., Madrid, 1995). Associate professor (1997) and full professor (2002) in Applied Mathematics at the Mathematics Department of the University of Castilla-La Mancha. Founding (2007-2012) and current (2016-) director of the Institute of Applied Mathematics in Science and Engineering (UCLM). Director of the department of mathematics (2005-2008, 2012-2016) at the same university. He has published more than 170 ISI-indexed research papers with 5800 citations and has an H-index of 40 (web of Science). He is editor in chief of "Physica D" and serves in the editorial boards of "Cancers", "European Radiology" and other journals. He is a member of the scientific committees of the Spanish Royal Society of Mathematics, the board of "Mathematical Action against coronavirus". He is a manager of Applied Mathematics at the Spanish National Research Agency. He has been a member of the Marie Curie evaluation committee and of many international project evaluation boards in oncology and/or applied mathematics in France, UK, Poland, Austria, Romania, Cyprus, Latvia, Spain, etc.
His main field of research is the application of mathematical modeling to oncology and more specifically to brain tumors, metastasis, cellular immunotherapies, biomarkers, medical images, lymphomas, leukaemias, prostate cancer, etc. In this field he leads several projects funded by public institutions, private foundations such as the James S. Mc. Donnell Foundation and pharmaceutical companies such as NOVARTIS. |
- Evolutionary dynamics at the tumor edge reveals metabolic imaging biomarkers
Proceedings of the National Academy of Sciences (USA) 118(6) e2018110118 (2021).
J. Jiménez-Sánchez, J.J. Bosque, G.A. Jiménez-Londoño, D. Molina-García, A. Martínez-Rubio, J. Pérez-Beteta, C. Ortega-Sabater, A.F Honguero-Martínez, A.M. García-Vicente, G.F. Calvo, V.M. Pérez-García - A Mathematical Description of the Bone Marrow Dynamics of CAR T-Cell Therapy in B-cell Childhood Acute Lymphoblastic Leukemia
International J. of Molecular Sciences 22, 6371 (2021)
A. Martínez-Rubio, S. Chulián, C. Blázquez Goñi, A. Pérez Martínez, M. Ramírez Orellana, A. Navarro-Zapata, C. Ferreras, V.M. Pérez-García, M. Rosa - A mesoscopic simulator to uncover heterogeneity and evolutionary dynamics in tumors
PLoS Computational Biology 17(2) e1008266 (2021).
J. Jiménez-Sánchez, A. Martínez-Rubio, A. Popov, J. Pérez-Beteta, Y. Azimzade, D. Molina-García, J. Belmonte-Beitia, G.F. Calvo, V.M. Pérez-García - Brain Metastasis Response to Stereotactic Radio Surgery: A Mathematical Approach
Mathematics 9(7) 716 (2021)
O. León-Triana, J. Pérez-Beteta, D. Albillo, A. Ortiz de Mendivil, L.A. Pérez-Romasanta, E. González del Portillo, M. Llorente, N. Carballo, E. Arana, V.M. Pérez-García - CAR T cell therapy in B-cell acute lymphoblastic leukaemia: Insights from mathematical models
Comm Nonlin Sci Numer Simul 94, 105570 (2021)
O. León-Triana, S. Sabir, G.F. Calvo, J. Belmonte-Beitia, S. Chulian, A. Martínez-Rubio, M. Rosa, A. Pérez-Martínez, M. Ramírez-Orellana, V.M. Pérez-García - CAR T cells for T-cell leukemias: Insights from mathematical models
Comm Nonlin Sci Numer Simul, 96, 105684 (2021)
V.M. Pérez-García, O. León-Triana, M. Rosa, A. Pérez-Martínez - Dual-Target Car-Ts With on- and off-Tumour Activity May Override Immune Suppression in Solid Cancers: A Mathematical Proof of Concept
Cancers 13, 703 (2021)
O. León-Triana, A. Pérez-Martínez, M. Ramírez-Orellana, V.M. Pérez-García - Dynamical properties of feedback signalling in B lymphopoiesis: A mathematical modelling approach
Journal of Theoretical Biology 110685 (2021)
S. Chulián, A. Martínez-Rubio, A. Marciniak-Czochra, T. Stiehl, C.B. Goñi, J.F. Rodríguez Gutiérrez, M.R. Orellana, A.C. Robleda, V.M. Pérez-García, M. Rosa - High-dimensional Analysis of Single-cell Flow Cytometry Data Predicts Relapse in Childhood Acute Lymphoblastic Leukemia
Cancers 13(1), 17 (2021).
S. Chulián, A. Martínez-Rubio, V.M. Pérez-García, M. Rosa, C. Blázquez-Goñi, J.F. Rodríguez Gutiérrez, L. Hermosín-Ramos, A. Molinos-Quintana, T. Caballero-Velázquez, M. Ramírez-Orellana, A. Castillo Robleda, J.L Fernández-Martínez - In vitro biomimetic models for glioblastoma-a promising tool for drug response studies
Drug Resistance Updates 55, 100753 (2021)
T. Stankovic, T. Randelovic, M. Dragoj, S.S. Buric, L. Fernández, I. Ochoa, V.M. Pérez-García, M. Pesic - Nonlinear science against the COVID-19 pandemic
Physica D 424 (2021) 132946
V.M. Pérez-García - Optimal Combinations of Chemotherapy and Radiotherapy in Low-Grade Gliomas: A Mathematical Approach
Journal of Personalized Medicine 2021, 11 (2021) 1036
L. E. Ayala-Hernández, A. Gallegos, P. Schucht, M. Murek, L. A. Pérez-Romasanta, J. Belmonte-Beitia, V. M. Pérez-García - The interplay of blood flow and temperature in regional hyperthermia: a mathematical approach
Royal Society Open Science 8, 201234 (2021)
J.J. Bosque, G.F. Calvo, V.M Pérez-García, M.C. Navarro
- Early identification of relapse and treatment optimization in acute lymphoblastic leukaemias through mathematical modelling and discriminant analysis
Junta de Andalucía (2020 - 2023) - Improving cell therapies in neuroblastoma through mathematical modelling
NeN Association (2020 - 2023) - Mathematical models in Oncology
Ministerio de Ciencia e Innovación (Spain) (2020 - 2023) - Mathematical models of tumor growth and response to therapies
Junta de Comunidades de Castilla-La Mancha (2018 - 2021) - Therapy Optimization in Glioblastoma: An integrative human data-based approach using mathematical models (Stage II)
James S. Mc. Donnell Foundation (USA) (2018 - 2021)