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Graduate (1991) PhD (Complutense U., Madrid, 1995). Associate professor (1997) and full professor (2002) in Applied Mathematics at the Mathematics Department of the University of Castilla-La Mancha. Founding (2007-2012) and current (2016-) director of the Institute of Applied Mathematics in Science and Engineering (UCLM). Director of the department of mathematics (2005-2008, 2012-2016) at the same university. He has published more than 170 ISI-indexed research papers with 5800 citations and has an H-index of 40 (web of Science). He is editor in chief of "Physica D" and serves in the editorial boards of "Cancers", "European Radiology" and other journals. He is a member of the scientific committees of the Spanish Royal Society of Mathematics, the board of "Mathematical Action against coronavirus". He is a manager of Applied Mathematics at the Spanish National Research Agency. He has been a member of the Marie Curie evaluation committee and of many international project evaluation boards in oncology and/or applied mathematics in France, UK, Poland, Austria, Romania, Cyprus, Latvia, Spain, etc.
His main field of research is the application of mathematical modeling to oncology and more specifically to brain tumors, metastasis, cellular immunotherapies, biomarkers, medical images, lymphomas, leukaemias, prostate cancer, etc. In this field he leads several projects funded by public institutions, private foundations such as the James S. Mc. Donnell Foundation and pharmaceutical companies such as NOVARTIS. |
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Metabolic Activity Grows in Human Cancers Pushed by Phenotypic Variability
iScience 26(3) 106118 (2023)
J.J. Bosque, G.F. Calvo, D. Molina-García, J. Pérez-Beteta, A.M. García Vicente, V. M. Pérez-García -
Stochastic Fluctuations Drive Non-genetic Evolution of Proliferation in Clonal Cancer Cell Populations
Bulletin of Mathematical Biology 85(1) 8 (2023)
C Ortega-Sabater, GF Calvo, Jelena Dinic, Ana Podolski, Milica Pesic, VM Perez-Garcia -
The shape of cancer relapse: Topological data analysis predicts recurrence in paediatric acute lymphoblastic leukaemia
(submitted, 2022)
S. Chulián, B. J. Stolz, A. Martínez-Rubio, C. Blázquez-Goñi, J. F. Rodríguez, T. Caballero, A. Molinos, M. Ramírez-Orellana, A. Castillo, J. L. Fuster, A. Minguela, M. V. Martínez, M. Rosa, V. M. Pérez-García, H. Byrne -
Growth dynamics of brain metastases differentiate radiation necrosis from recurrence
Neurooncology Advances (2022) vdac179
B. Ocaña-Tienda, J. Pérez-Beteta, D. Molina-García, B. Asenjo, A. Ortiz de Mendivil, D. Albillo, LA Pérez-Romasanta, E. González del Portillo, M. Llorente, N. Carballo, E. Arana, Víctor M Pérez-García -
Mathematical models of leukaemia and its treatment: a review
SEMA Journal 79, 441-486 (2022)
S. Chulián, Á. Martínez-Rubio, M. Rosa, V. M. Pérez-García -
Multiple and diffuse gliomas by 18F-Fluorocholine PET/CT: two sides of the same coin
Clinical Nuclear Medicine 47(6), e457-e465 (2022)
A. M. García Vicente, J. Pérez-Beteta, J. J. Bosque, A. M. Soriano, V. M. Pérez-García -
On optimal temozolomide scheduling for slowly growing glioblastomas
Neuro-Oncology Advances 4(1), vdac155, 1-13 (2022)
B. Segura-Collar, J. Jiménez-Sánchez, R. Gargini, M. Dragoj, J. M. Sepúlveda, M. Pesic, M. A. Ramírez, L. E. Ayala-Hernández, P.Sánchez-Gómez, V. M Pérez-García -
Patient-specific forecasting of post-radiotherapy prostate-specific antigen kinetics enables early prediction of biochemical relapse
iScience 25, 105430 (2022)
G. Lorenzo, N. di Muzio, C. L. Deantoni, C. Cozzarini, A. Fodor, A. Briganti, F. Montorsi, V. M. Pérez-García, H. Gómez, A. Reali -
SUVmax to tumor perimeter distance: a robust radiomics prognostic biomarker in resectable non-small cell lung cancer patients
European Radiology 32, 3889-3902 (2022)
G. A. Jiménez-Londoño, A. M. García Vicente, J. J. Bosque, M. Amo-Salas, J. Pérez-Beteta, A. F. Honguero-Martinez, V. M. Pérez-García, A. M. Soriano -
The Macroscopic Growth Laws of Brain Metastases
medrxiv (submitted for publication, 2022)
B. Ocaña-Tienda, J. Pérez-Beteta, D. Molina-García, J. Jiménez-Sánchez, O. Leon-Triana, A. Ortiz de Mendivil, B. Asenjo, D. Albillo, L. Pérez-Romasanta, M. Valiente, L. Zhu, P. García- Gómez, E. González-Del Portillo, M. Llorente, N. Carballo, E. Arana, V. M. Pérez-García
- Early identification of relapse and treatment optimization in acute lymphoblastic leukaemias through mathematical modelling and discriminant analysis
Junta de Andalucía (2020 - 2023) - Improving cell therapies in neuroblastoma through mathematical modelling
NeN Association (2020 - 2023) - Mathematical models in Oncology
Ministerio de Ciencia e Innovación (Spain) (2020 - 2023) - Mathematical models of tumor growth and response to therapies
Junta de Comunidades de Castilla-La Mancha (2018 - 2021) - Therapy Optimization in Glioblastoma: An integrative human data-based approach using mathematical models (Stage II)
James S. Mc. Donnell Foundation (USA) (2018 - 2021)

Graduate (1991) PhD (Complutense U., Madrid, 1995). Associate professor (1997) and full professor (2002) in Applied Mathematics at the Mathematics Department of the University of Castilla-La Mancha. Founding (2007-2012) and current (2016-) director of the Institute of Applied Mathematics in Science and Engineering (UCLM). Director of the department of mathematics (2005-2008, 2012-2016) at the same university. He has published more than 170 ISI-indexed research papers with 5800 citations and has an H-index of 40 (web of Science). He is editor in chief of "Physica D" and serves in the editorial boards of "Cancers", "European Radiology" and other journals. He is a member of the scientific committees of the Spanish Royal Society of Mathematics, the board of "Mathematical Action against coronavirus". He is a manager of Applied Mathematics at the Spanish National Research Agency. He has been a member of the Marie Curie evaluation committee and of many international project evaluation boards in oncology and/or applied mathematics in France, UK, Poland, Austria, Romania, Cyprus, Latvia, Spain, etc.
His main field of research is the application of mathematical modeling to oncology and more specifically to brain tumors, metastasis, cellular immunotherapies, biomarkers, medical images, lymphomas, leukaemias, prostate cancer, etc. In this field he leads several projects funded by public institutions, private foundations such as the James S. Mc. Donnell Foundation and pharmaceutical companies such as NOVARTIS. |
- Metabolic Activity Grows in Human Cancers Pushed by Phenotypic Variability
iScience 26(3) 106118 (2023)
J.J. Bosque, G.F. Calvo, D. Molina-García, J. Pérez-Beteta, A.M. García Vicente, V. M. Pérez-García - Stochastic Fluctuations Drive Non-genetic Evolution of Proliferation in Clonal Cancer Cell Populations
Bulletin of Mathematical Biology 85(1) 8 (2023)
C Ortega-Sabater, GF Calvo, Jelena Dinic, Ana Podolski, Milica Pesic, VM Perez-Garcia - The shape of cancer relapse: Topological data analysis predicts recurrence in paediatric acute lymphoblastic leukaemia
(submitted, 2022)
S. Chulián, B. J. Stolz, A. Martínez-Rubio, C. Blázquez-Goñi, J. F. Rodríguez, T. Caballero, A. Molinos, M. Ramírez-Orellana, A. Castillo, J. L. Fuster, A. Minguela, M. V. Martínez, M. Rosa, V. M. Pérez-García, H. Byrne - Growth dynamics of brain metastases differentiate radiation necrosis from recurrence
Neurooncology Advances (2022) vdac179
B. Ocaña-Tienda, J. Pérez-Beteta, D. Molina-García, B. Asenjo, A. Ortiz de Mendivil, D. Albillo, LA Pérez-Romasanta, E. González del Portillo, M. Llorente, N. Carballo, E. Arana, Víctor M Pérez-García - Mathematical models of leukaemia and its treatment: a review
SEMA Journal 79, 441-486 (2022)
S. Chulián, Á. Martínez-Rubio, M. Rosa, V. M. Pérez-García - Multiple and diffuse gliomas by 18F-Fluorocholine PET/CT: two sides of the same coin
Clinical Nuclear Medicine 47(6), e457-e465 (2022)
A. M. García Vicente, J. Pérez-Beteta, J. J. Bosque, A. M. Soriano, V. M. Pérez-García - On optimal temozolomide scheduling for slowly growing glioblastomas
Neuro-Oncology Advances 4(1), vdac155, 1-13 (2022)
B. Segura-Collar, J. Jiménez-Sánchez, R. Gargini, M. Dragoj, J. M. Sepúlveda, M. Pesic, M. A. Ramírez, L. E. Ayala-Hernández, P.Sánchez-Gómez, V. M Pérez-García - Patient-specific forecasting of post-radiotherapy prostate-specific antigen kinetics enables early prediction of biochemical relapse
iScience 25, 105430 (2022)
G. Lorenzo, N. di Muzio, C. L. Deantoni, C. Cozzarini, A. Fodor, A. Briganti, F. Montorsi, V. M. Pérez-García, H. Gómez, A. Reali - SUVmax to tumor perimeter distance: a robust radiomics prognostic biomarker in resectable non-small cell lung cancer patients
European Radiology 32, 3889-3902 (2022)
G. A. Jiménez-Londoño, A. M. García Vicente, J. J. Bosque, M. Amo-Salas, J. Pérez-Beteta, A. F. Honguero-Martinez, V. M. Pérez-García, A. M. Soriano - The Macroscopic Growth Laws of Brain Metastases
medrxiv (submitted for publication, 2022)
B. Ocaña-Tienda, J. Pérez-Beteta, D. Molina-García, J. Jiménez-Sánchez, O. Leon-Triana, A. Ortiz de Mendivil, B. Asenjo, D. Albillo, L. Pérez-Romasanta, M. Valiente, L. Zhu, P. García- Gómez, E. González-Del Portillo, M. Llorente, N. Carballo, E. Arana, V. M. Pérez-García
- Early identification of relapse and treatment optimization in acute lymphoblastic leukaemias through mathematical modelling and discriminant analysis
Junta de Andalucía (2020 - 2023) - Improving cell therapies in neuroblastoma through mathematical modelling
NeN Association (2020 - 2023) - Mathematical models in Oncology
Ministerio de Ciencia e Innovación (Spain) (2020 - 2023) - Mathematical models of tumor growth and response to therapies
Junta de Comunidades de Castilla-La Mancha (2018 - 2021) - Therapy Optimization in Glioblastoma: An integrative human data-based approach using mathematical models (Stage II)
James S. Mc. Donnell Foundation (USA) (2018 - 2021)