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Carmen Ortega-Sabater (BSc in Biology and MSc in Experimental Oncology, University of Murcia, and MSc in Applied Mathematics, University of Castilla-La Mancha) is a Ph.D. student funded by the Spanish Association Against Cancer (AECC). She is studying mathematically the mechanisms behind phenotypic plasticity and also malignancy evolution in pediatric leukemias and brain metastases using single-cell karyotyping and scRNA-seq data and working in collaboration with Josep Carreras Leukemia Research Institute and CNIO. |
Publications
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A glance at evolvability: a theoretical analysis of its role in the evolutionary dynamics of cell populations
arXiv:2402.06392
J. Jiménez-Sánchez, C. Ortega-Sabater, P. K. Maini, V.M. Pérez-García, T. Lorenzi -
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression
EMBO Molecular Medicine 16, 64-92 (2024)
O Molina, C Ortega-Sabater, N Thampi, N Fernández, M Guerrero, A Martínez, M Vinyoles, T Velasco, C Bueno, JL Trincado, I Granada, D Campos, C Giménez, JM Boer , ML den Boer, GF Calvo, Mireia Camós, JL Fuster P Velasco, P Ballerini, F Locatelli, CG Mullighan, DCJ Spierings, F Foijer, VM Pérez-García, P Menéndez -
Stochastic Fluctuations Drive Non-genetic Evolution of Proliferation in Clonal Cancer Cell Populations
Bulletin of Mathematical Biology 85(1) 8 (2023)
C Ortega-Sabater, GF Calvo, Jelena Dinic, Ana Podolski, Milica Pesic, VM Perez-Garcia -
Evolutionary dynamics at the tumor edge reveals metabolic imaging biomarkers
Proceedings of the National Academy of Sciences (USA) 118(6) e2018110118 (2021).
J. Jiménez-Sánchez, J.J. Bosque, G.A. Jiménez-Londoño, D. Molina-García, A. Martínez-Rubio, J. Pérez-Beteta, C. Ortega-Sabater, A.F Honguero-Martínez, A.M. García-Vicente, G.F. Calvo, V.M. Pérez-García
Projects
- Integrative CellOmics for precision medicine in childhood leukemia: A coordinated eHealth action for cancer biodigitization (LEUKODOMICS)
Ministery of Science and Innovation (NextGenerationEU) (2023 - 2024) - Improving New Therapies in Oncology and Related Fields using mathematical models and biomedical data
Ministry of Science and Innovation (National Research Plan) (2023 - 2026) - Mathematical models for the digital transition in neuro-oncology: In-silico design of a clinical trial for glioblastoma.
Ministerio de Ciencia e Innovación (NextGenerationEU) (2023 - 2024) - Validation and transfer of oncological data and biomarkers based on mathematical models (AFTERbioMATH)
Ministry of Science and Innovation (Spain), Proof of Concept Program (2023 - 2024) - Mathematical models in Oncology
Ministerio de Ciencia e Innovación (Spain) (2020 - 2023)
Ortega Sabater, Carmen
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Carmen Ortega-Sabater (BSc in Biology and MSc in Experimental Oncology, University of Murcia, and MSc in Applied Mathematics, University of Castilla-La Mancha) is a Ph.D. student funded by the Spanish Association Against Cancer (AECC). She is studying mathematically the mechanisms behind phenotypic plasticity and also malignancy evolution in pediatric leukemias and brain metastases using single-cell karyotyping and scRNA-seq data and working in collaboration with Josep Carreras Leukemia Research Institute and CNIO. |
Publications
- A glance at evolvability: a theoretical analysis of its role in the evolutionary dynamics of cell populations
arXiv:2402.06392
J. Jiménez-Sánchez, C. Ortega-Sabater, P. K. Maini, V.M. Pérez-García, T. Lorenzi - Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression
EMBO Molecular Medicine 16, 64-92 (2024)
O Molina, C Ortega-Sabater, N Thampi, N Fernández, M Guerrero, A Martínez, M Vinyoles, T Velasco, C Bueno, JL Trincado, I Granada, D Campos, C Giménez, JM Boer , ML den Boer, GF Calvo, Mireia Camós, JL Fuster P Velasco, P Ballerini, F Locatelli, CG Mullighan, DCJ Spierings, F Foijer, VM Pérez-García, P Menéndez - Stochastic Fluctuations Drive Non-genetic Evolution of Proliferation in Clonal Cancer Cell Populations
Bulletin of Mathematical Biology 85(1) 8 (2023)
C Ortega-Sabater, GF Calvo, Jelena Dinic, Ana Podolski, Milica Pesic, VM Perez-Garcia - Evolutionary dynamics at the tumor edge reveals metabolic imaging biomarkers
Proceedings of the National Academy of Sciences (USA) 118(6) e2018110118 (2021).
J. Jiménez-Sánchez, J.J. Bosque, G.A. Jiménez-Londoño, D. Molina-García, A. Martínez-Rubio, J. Pérez-Beteta, C. Ortega-Sabater, A.F Honguero-Martínez, A.M. García-Vicente, G.F. Calvo, V.M. Pérez-García
Projects
- Integrative CellOmics for precision medicine in childhood leukemia: A coordinated eHealth action for cancer biodigitization (LEUKODOMICS)
Ministery of Science and Innovation (NextGenerationEU) (2023 - 2024) - Improving New Therapies in Oncology and Related Fields using mathematical models and biomedical data
Ministry of Science and Innovation (National Research Plan) (2023 - 2026) - Mathematical models for the digital transition in neuro-oncology: In-silico design of a clinical trial for glioblastoma.
Ministerio de Ciencia e Innovación (NextGenerationEU) (2023 - 2024) - Validation and transfer of oncological data and biomarkers based on mathematical models (AFTERbioMATH)
Ministry of Science and Innovation (Spain), Proof of Concept Program (2023 - 2024) - Mathematical models in Oncology
Ministerio de Ciencia e Innovación (Spain) (2020 - 2023)
