Imaging Biomarkers in Glioblastoma

Glioblastoma is the most frequent and aggressive malignant primary brain tumor, with patient median survival of only 14 months from diagnosis. High resolution magnetic resonance imaging is routine for diagnosis, treatment planning, response evaluation and follow-up. We reconstruct the tumors in 3D and use mathematics to identify ‘hidden’ features (e.g. morphological or textural properties) related to patient prognosis and allowing to personalize treatments.


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Imaging biomarkers in glioblastoma is a multidisciplinary research line with an extensive database of high-quality medical images, clinical information, and the participation of clinical personnel from different services of the following institutions:  Hospital 12 de Octubre de Madrid (Spain),  Hospital General de Ciudad Real (Spain),  Hospital Universitario Marqués de Valdecilla de Santander (Spain), Hospital Universitario de Toledo (Spain), Hospital Regional Universitario de Málaga (Spain), Hospital Universitario de Salamanca (Spain), Hospital de Manises (Spain) and Toronto Western Hospital (Canada).