Publications
 
 								
				
					  						
                          
							 
					  
                            A Mathematical Model for Fibrous Dysplasia: The Role of the Flow of Mutant Cells                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            M. Soloviova, J.C. Beltrán-Vargas, L. Fernández De Castro, J. Belmonte-Beitia, V.M. Pérez-García, M. Caballero                     
                                  
                     
					 
                            Bulletin of Mathematical Biology 86, 108 (2024)					 
				 
 								
				
					  						
                          
							 
					  
                            A mathematical model of CAR-T cell therapy in combination with chemotherapy for malignant gliomas                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            Dmitry Sinelshchikov, Juan Belmonte-Beitia, Matteo Italia.                     
                                  
                     
					 
                            Chaos 35, 063104 (2025)					 
				 
 								
				
					  						
                          
							 
					  
                            Analytical performance validation of aPROMISE platform for prostate tumor burden                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            García Vicente, A.M., Lucas Lucas, C., Pérez-Beteta, J. et al.                      
                                  
                     
					 
                            Scientific Reports 14, 3001 (2024)					 
				 
 								
				
					  						
                          
							 
					  
                            Asymptotic dynamics and optimal treatment for a model of tumour resistance to chemotherapy                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            Mariusz Bodzioch, Juan Belmonte-Beitia, Urszula Forys                     
                                  
                     
					 
                            Applied Mathematical Modelling, 135 (2024), 620-639					 
				 
 								
				
					  						
                          
							 
					  
                            Automatic computational classification of bone marrow cells for B cell pediatric leukemia using UMAP                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            Ana Niño-López, Álvaro Martínez-Rubio, Rocío Picón-González, Ana Castillo Robleda, Manuel Ramírez Orellana, Salvador Chulián & María Rosa                      
                                  
                     
					 
                            BioData Mining 18, 73 (2025)					 
				 
 								
				
					  						
                          
							 
					  
                            Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            O Molina, C Ortega-Sabater, N Thampi, N Fernández, M Guerrero, A Martínez, M Vinyoles, T Velasco, C Bueno, JL Trincado, I Granada, D Campos, C Giménez, JM Boer , ML den Boer, GF Calvo, Mireia Camós, JL Fuster P Velasco, P Ballerini, F Locatelli, CG Mullighan, DCJ Spierings, F Foijer, VM Pérez-García, P Menéndez                     
                                  
                     
					 
                            EMBO Molecular Medicine 16, 64-92 (2024)					 
				 
 								
				
					  						
                          
							 
					  
                            Clinicopathologic and metabolic variables from 18F-FDG PET/CT in the prediction of recurrence pattern in stage I-III non-small-cell lung cancer after curative surgery.                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            G. Jiménez-Londoño, J. Pérez-Beteta, M. Amo-Salas, A. Honguero, V M. Pérez-García, C. Lucas, A. M. Soriano, A. M. García-Vicente                     
                                  
                     
					 
                            Annals of Nuclear Medicine 9 (2025)					 
				 
 								
				
					  						
                          
							 
					  
                            Computational flow cytometry immunophenotyping at diagnosis is unable to predict relapse in childhood B-cell Acute Lymphoblastic Leukemia                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            A. Martínez, S. Chulián, A. Niño, R. Picón, J. F. Rodríguez, E. Gálvez, T. Caballero, A. Molinos, A. Castillo, M. Ramírez, M. V. Martínez, A. Míguela, J. L. Fuster, C. Blázquez, V. M. Pérez-García, M. Rosa                     
                                  
                     
					 
                            Computers in Biology and Medicine 188, 109831 (2025).					 
				 
 								
				
					  						
                          
							 
					  
                            Deterministic reprogramming of neutrophils within tumors                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            M.S.F. Ng, I. Kwok, L. Tan, C. Shi, D. Cerezo, Y. Tan, K. Leong, G.F. Calvo, K. Yang, Y. Zhang, J. Jin, K.H. Liong, D. Wu, R. He, ..., A. Hidalgo, F. Ginhoux, L.G. Ng                     
                                  
                     
					 
                            Science 383, eadf6493 (2024) 					 
				 
 								
				
					  						
                          
							 
					  
                            Dual CAR-T cell therapy for glioblastoma:  strategies to cure tumour diseases based on a mathematical model                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            M. Bodnar, M.J. Piotrowska, M. Bodzioch, J. Belmonte-Beitia, U. Forys                     
                                  
                     
					 
                            Nonlinear Dynamics 113, 1637–1666 (2025)					 
				 
 								
				
					  						
                          
							 
					  
                            Exploring neuroblastoma’s cellular microenvironment: A novel approach using cellular automata to model Celyvir treatment                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            José García Otero, Juan Belmonte-Beitia, Juan Jiménez-Sánchez                     
                                  
                     
					 
                            Computers in Biology and Medicine 188, 109782 (2025)					 
				 
 								
				
					  						
                          
							 
					  
                            Geometric immunosuppression in CAR T-cell treatment: Insights from mathematical modeling                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            S. Bordel-Vozmediano, S. Sabir, L. Benito-Barca, B. Weigelin, V. M. Pérez-García                     
                                  
                     
					 
                            Computers in Biology and Medicina 194, 110427 (2025)					 
				 
 								
				
					  						
                          
							 
					  
                            Growth dynamics of lung nodules: implications for classification in lung cancer screening                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            B. Ocaña-Tienda, A. Eroles-Simó, J. Pérez-Beteta, E. Arana, V. M. Pérez-García                     
                                  
                     
					 
                            Cancer Imaging 24, 113 (2024)					 
				 
 								
				
					  						
                          
							 
					  
                            Influence of time delay on the dynamics of a mathematical model of CAR-T                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            M. Szafranska, M. Bodnar, M. J. Piotrowska, M. Krukowski, J. Belmonte-Beitia, U. Forys                     
                                  
                     
					 
                            Discrete and continuous Dynamical Systems B 38(11), 4498-4515 (2025)					 
				 
 								
				
					  						
                          
							 
					  
                            Integrated modeling of labile and glycated hemoglobin with glucose for enhanced diabetes detection and short-term monitoring                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            Romero-Rosales JA, Aragones DG, Escribano-Serrano J, Borrachero MG, Doña AM, Macías López FJ, Santos Mata MA, Jiménez IN, Casamitjana Zamora MJ, Serrano H, Belmonte-Beitia J, Durán MR, Calvo GF                     
                                  
                     
					 
                            iScience. 27(4), 109369 (2024)					 
				 
 								
				
					  						
                          
							 
					  
                            Mathematical model of CAR T-cell therapy for a B-cell Lymphoma lymph node                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            Soukaina Sabir, Odelaisy León-Triana, Sergio Serrano, Roberto Barrio, Victor M. Pérez-García                     
                                  
                     
					 
                            Bulletin of Mathematical Biology 87, 40 (2025)					 
				 
 								
				
					  						
                          
							 
					  
                            Mathematical model of tumor macrophage dynamics in glioma to advance myeloid-targeted therapies                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            Jesús J. Bosque, Jordan Martínez, José García Otero, Guim Aguadé, Javier Sánchez, Juan Belmonte-Beitia                     
                                  
                     
					 
                            Computers in Biology and Medicine, Volume 196, Part C, 2025, 110909					 
				 
 								
				
					  						
                          
							 
					  
                            Mathematical modeling of brain metastases growth and response to therapies: A review                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            Beatriz Ocaña-Tienda, Víctor M. Pérez-García                     
                                  
                     
					 
                            Mathematical Biosciences 373, 109207 (2024)					 
				 
 								
				
					  						
                          
							 
					  
                            Modeling Fibrous Dysplasia Progression and its Therapeutic Intervention                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            Juan C. Beltran-Vargas, Luis F. de Castro, Gabriel F. Calvo and Victor M. Pérez-García                     
                                  
                     
					 
                            Mathematical Modeling of Natural Phenomena 20, 3 (2025)					 
				 
 								
				
					  						
                          
							 
					  
                            Morphological MRI features as prognostic indicators in brain metastases                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            Ocaña-Tienda B, Pérez-Beteta J, Ortiz de Mendivil A, Asenjo B, Albillo D, Pérez-Romasanta LA, LLorente M, Carballo N, Arana E, Pérez-García VM.                     
                                  
                     
					 
                            Cancer Imaging 24, 111 (2024)					 
				 
 								
				
					  						
                          
							 
					  
                            On the Dynamics and Optimal Control of a Mathematical Model of Neuroblastoma and its Treatment: Insights from a Mathematical Model                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            José García Otero, Mariusz Bodzioch, and Juan Belmonte-Beitia                     
                                  
                     
					 
                            M3AS: Mathematical Models and Methods in Applied Sciences  07(34) (2024)					 
				 
 								
				
					  						
                          
							 
					  
                            Optimal control of a mathematical model of CAR-T cell therapy for glioblastoma.                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            Mariusz Bodzioch, Juan Belmonte-Beitia                     
                                  
                     
					 
                             Discrete and Continuous Dynamical Systems - B, 2025, 30(11): 4255-427					 
				 
 								
				
					  						
                          
							 
					  
                            Radiation necrosis after radiation therapy treatment of brain metastases: A computational approach                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            Beatriz Ocana-Tienda, Odelaisy Leon-Triana, Julian Perez-Beteta,  Juan Jiménez-Sánchez, Victor M. Perez-Garcia                     
                                  
                     
					 
                            PLOS Computational Biology 20(1) e1011400 (2024)					 
				 
 								
				
					  						
                          
							 
					  
                            Understanding the role of B cells in CAR T-cell therapy in leukemia through a mathematical model                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            S. Serrano, R. Barrio, A. Martínez-Rubio, J. Belmonte-Beitia, V. M. Pérez-García                     
                                  
                     
					 
                            Chaos 34, 083142 (2024)					 
				 
 								
				
					  						
                          
							 
					  
                            Variable selection for dimensionality reduction of biological datasets through bootstrapping of correlation networks                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            D.G. Aragones, M. Palomino, J. Sicilia, G. Crainiciuc, I. Ballesteros, F. Sánchez-Cabo, A. Hidalgo, G.F. Calvo                     
                                  
                     
					 
                            Computers in Biology and Medicine 168, 107827 (2024).					 
				 
 								
				
					  						
                          
							 
					  
                            Volumetric Analysis: Rethinking Brain Metastases Response Assessment                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            B Ocaña-Tienda, J Pérez-Beteta, JA Romero-Rosales, B Asenjo, A Ortiz, LA Pérez Romasanta, JD Albillo, F Nagib, M Vidal Denis, B. Luque, E. Arana, VM Pérez-García                     
                                  
                     
					 
                            Neuro-Oncoloy Advances 6(1), 1-9 (2024)					 
				 
 								
				
					  						
                          
							 
					  
                            A glance at evolvability: a theoretical analysis of its role in the evolutionary dynamics of cell populations                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            J. Jiménez-Sánchez, C. Ortega-Sabater, P. K. Maini, V.M. Pérez-García, T. Lorenzi                     
                                  
                     
					 
                            arXiv:2402.06392					 
				 
 								
				
					  						
                          
							 
					  
                            Synergistic interplay of morphology and metabolic activity rule response to CAR-T cells in B-cell lymphomas                       
                          
						 
                     
	
                    
						 
                       
				 
             
                            Y Chen, S Sabir, C Kuttler, J Belmonte,  A Martinez, L Martin, L Lopez-Corral,  A Martin-Sancho, JC Cañadas, C Montes, M. PTamayo,  A Cedillo, P Balsalobre, P Barba, A Pérez-Martínez, VM Pérez-García                     
                                  
                     
					 
                            arXiv:2505.11894					 
				 
								 
								 
								 
								 
								 
											 
								 
								 
								 
								 
								 
								 
								 
								